N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-1-piperazinamine
304909-07-7
373.5
C23H27N5
DMF, DMSO, Ethanol
-20°C
SANT-1 is a cell-permeable, potent inhibitior of Sonic hedgehog (Shh) signaling; high affinity antagonist of smoothened activity (Kd = 1.2 nM). Inhibits smoothened agonist effects with an ICof 20 nM in Shh-LIGHT2 cells. SANT-1 inhibits both wild type and oncogenic Smo with equal potency.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
